Mfn2 polyclonal antibody

CAT: 0384-BS71425-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS71425-01Size:50 µL
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Background
This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
HSG; MARF; CMT2A; CPRP1; CMT2A2
Swiss Prot
O95140
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human MFN2.
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB: 1:500~1:2000 IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 86 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Mfn2 polyclonal antibody detects endogenous levels of Mfn2 protein.
Applications Notes
Western blot analysis of extracts of various cells, using MFN2 antibody.
Host or Source
Rabbit

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