CBLC polyclonal antibody

• Background:

  This gene encodes a member of the Cbl family of E3 ubiquitin ligases. Cbl proteins play important roles in cell signaling through the ubiquitination and subsequent downregulation of tyrosine kinases. Expression of this gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

• Structure Composition:

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  CBL-3; RNF57; CBL-SL

• Swiss Prot:

  Q9ULV8

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant protein of human CBLC.

• Conjugation:

  Unconjugated

• Applications:

  WB IF

• Dilution:

  WB 1:500 - 1:2000 IF 1:50 - 1:100

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodification

• Molecular Weight:

  ~ 52 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  CBLC polyclonal antibody detects endogenous levels of CBLC protein.

• Applications Notes:

  Western blot analysis of extracts of various cells, using CBLC antibody.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4