IL13 polyclonal antibody

CAT: 0384-BS6637-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS6637-01Size:50 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Interleukin-13, or IL-13, is a pleiotropic cytokine that exhibits 30% sequence identity with IL-4 and shares many of the same biological activities. Like IL-4, IL-13 affects monocytes, macrophages and B cells by upregulating the expression of CD23 and MHC proteins, and downregulating the expression of CD14. Both IL-4 and IL-13 are secreted by activated T lymphocytes and are powerful regulators of inflammation. Both inhibit the secretion of proinflammatory cytokines and chemokines from activated monocytes and stimulate the expression of IgE on activated B cells. IL-13 contains five Cysteine residues and multiple N-linked glycosylation sites and has been reported to inhibit the production of IL-2 in natural killer cells. IL-13 cDNA encodes a 131 amino acid precursor with a 20 amino acid signal peptide which is cleaved to generate a mature protein.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Allergic rhinitis; ALRH; BHR1; Bronchial hyperresponsiveness 1 (bronchial asthma) ; IL 13; IL-13; Il13; IL13; Interleukin 13; Interleukin-13; MGC116786; MGC116788; MGC116789; NC30; P600
Swiss Prot
P35225
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full length Human IL13.
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB: 1:500~1:2000 IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 16 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IL13 polyclonal antibody detects endogenous levels of IL13 protein.
Applications Notes
Western blot analysis of extracts of recombinant protein using IL13 antibody.
Host or Source
Rabbit

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