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CD200R1 polyclonal antibody

CAT: 0384-BS61747-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS61747-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
OX2 (CD200, MOX2), a member of the immunoglobulin superfamily (IgSF), is a 248-residue cell surface glycoprotein that is expressed in lymphoid cells, neurons and endothelium. OX2 receptor (OX2R) is a membrane protein with up to 70% of its weight derived from N-linked glycosylation, and it is primarily expressed in lymphoid and neuronal tissue. Phylogenetic analysis of OX2R with respect to other leukocyte IgSF glycoproteins suggests that OXR2 and OX2 share a common ancestral protein. The cytoplasmic portion of OX2R contains NPXY motifs that are known to interact with PTB/PID binding domains. The interaction between OX2 and OX2R may contribute to pathways that suppress and limit macrophage induced inflammatory damage in tissue.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Cell surface glycoprotein CD200 receptor 1; CD200 cell surface glycoprotein receptor; Cell surface glycoprotein OX2 receptor 1; CD200R1; CD200R; CRTR2; MOX2R; OX2R; UNQ2522; PRO6015
Swiss Prot
Q8TD46
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 250-300 of Human CD200R1.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 36 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CD200R1 polyclonal antibody detects endogenous levels of CD200R1 protein.
Applications Notes
Western blot (WB) analysis of CD200R1 polyclonal antibody at 1:1000 dilution Lane1:L02 whole cell lysate (40ug) Lane2:A549 whole cell lysate (40ug) Lane3:AML-12 whole cell lysate (40ug) Lane4:H9C2 whole cell lysate (40ug)
Host or Source
Rabbit

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