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SAR1B polyclonal antibody

CAT: 0384-BS61634-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS61634-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
There are a number of components involved in the secretory pathway of cells. Vesicular traffic within the early secretory pathway is mediated by COPI- and COPII-coated vesicles. The COPII vesicle coat protein promotes the formation of endoplasmic reticulum (ER) derived transport vesicles that carry secretory proteins to the Golgi complex. The SAR1 gene encodes two isoforms, Sar1a and Sar1B, in mammalian cells. These proteins are low-molecular-weight GTPases, which are essential for the formation of transport vesicles from the ER. Mutations in the SAR1 gene result in Anderson’s disease (and/or chylomicron retention disease CMRD), a rare, autosomal recessive lipid malabsorption disorder characterized by chronic diarrhea, failure to thrive and hypocholesterolemia in childhood.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
GTP-binding protein B; GTBPB; GTP-binding protein SAR1b; SAR1B; SARA2, SARB
Swiss Prot
Q9Y6B6
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding Human SAR1B.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 22 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
SAR1B polyclonal antibody detects endogenous levels of SAR1B protein.
Applications Notes
Western blot (WB) analysis of SAR1B polyclonal antibody at 1:500 dilution Lane1:The Brain tissue lysate of Mouse (40ug) Lane2:The Brain tissue lysate of Rat (40ug) Lane3:HepG2 whole cell lysate (40ug) Lane4:HCT116 whole cell lysate (40ug)
Host or Source
Rabbit

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