APOOL polyclonal antibody

• Background:

  Apolipoproteins are a family of fatty-acid binding proteins that transport fat through the bloodstream in the form of lipoproteins. ApoO functions to promote the transport of cholesterol from macrophage cells and may be involved in regulatory mechanisms that protect lipid accumulation within the heart. ApoO is present in high density lipoproteins (HDLs) and low density lipoproteins (LDLs), and is secreted by an MTP (microsomal triglyceride transfer protein) -dependent mechanism. ApoOL (apolipoprotein O-like), also known as FAM121A, is a 268 amino acid secreted protein belonging to the apolipoprotein O family and may be involved in cholesterol transport. ApoOL is encoded by a gene located on human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes.

• Structure Composition:

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  MICOS complex subunit MIC27; Apolipoprotein O-like; Protein FAM121A

• Swiss Prot:

  Q6UXV4

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic peptide, corresponding to amino acids 224-268 of Human APOOL

• Conjugation:

  Unconjugated

• Applications:

  WB

• Dilution:

  WB: 1:500~1:1000

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)

• Modification:

  Unmodification

• Molecular Weight:

  ~ 34 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  APOOL polyclonal antibody detects endogenous levels of APOOL protein.

• Applications Notes:

  Western blot (WB) analysis of APOOL polyclonal antibody at 1:500 dilution Lane1:HCT116 whole cell lysate (40ug) Lane2:SK-OVCAR3 whole cell lysate (40ug) Lane3:PC3 whole cell lysate (40ug) Lane4:The Kidney lysate of Rat (40ug) Lane5:The Kidney lysate of Mouse (40ug)

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4