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NTPCR polyclonal antibody

CAT: 0384-BS61566-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS61566-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Belonging to the THEP1 NTPase family, C1orf57 (also known as nucleoside triphosphate phosphohydrolase), and its mouse homolog, 2310079N02Rik, are 190 amino acid proteins that has nucleotide phosphatase activity towards ATP, GTP, TTP, CTP and UTP. Acting as a monomer, it also hydrolyzes nucleoside diphosphates with lower efficiency. The gene encoding C1orf57 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Cancer-related nucleoside-triphosphatase; NTPase; Nucleoside triphosphate phosphohydrolase
Swiss Prot
Q9BSD7
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 145-189 of Human NTPCR
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
Modification
Unmodification
Molecular Weight
~ 21 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
NTPCR polyclonal antibody detects endogenous levels of NTPCR protein.
Applications Notes
Western blot (WB) analysis of NTPCR polyclonal antibody at 1:500 dilution Lane1:HCT116 whole cell lysate (40ug) Lane2:HCC827 whole cell lysate (40ug) Lane3:L02 whole cell lysate (40ug) Lane4:SK-OVCAR3 whole cell lysate (40ug)
Host or Source
Rabbit

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