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ZNF839 polyclonal antibody

CAT: 0384-BS61488-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS61488-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ZNF839, also known as C14orf131, is an 811 amino acid protein that contains one C2H2-type zinc finger. The gene encoding ZNF839 localizes to chromosome 14 and, due to alternative splicing events, four ZNF839 isoforms are expressed. Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder å1-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein BCL3 in the (14;19) translocations found in a variety of B cell malignancies.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Zinc finger protein 839; Renal carcinoma antigen NY-REN-50; ZNF839
Swiss Prot
A8K0R7
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 44-89 of Human ZNF839.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 80 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
ZNF839 polyclonal antibody detects endogenous levels of ZNF839 protein.
Applications Notes
Western blot (WB) analysis of ZNF839 polyclonal antibody at 1:500 dilution Lane1:H9C2 whole cell lysate (40ug) Lane2:RAW264.7 whole cell lysat (40ug) Lane3:Hela whole cell lysate (40ug)
Host or Source
Rabbit

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