ABCA9 polyclonal antibody

CAT: 0384-BS61300-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS61300-01Size:50 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ABCA9 (ATP-binding cassette, sub-family A (ABC1), member 9) is a 1,624 amino acid protein belonging to the ABC transporter superfamily and the ABCA family. The ABC1 subfamily is the only major ABC subfamily exclusive to multicellular eukaryotes. Ubiquitously expressed, with high expression in heart, brain and fetal tissues, ABCA9 is a multi-pass membrane protein that contains two ABC transporter domains and exists as five alternatively spliced isoforms. ABCA9 exhibits membrane subcellular localization and may play a role in monocyte differentiation and lipid homeostasis. ABCA9 is up-regulated during monocyte differentiation into macrophages and down-regulated by cholesterol loading of macrophages. Spanning 85 kb, ABCA9 contains 39 exons, with a non-coding first exon. ABCA9 is one of five ABC1 family members that maps to human chromosome 17q24.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
ATP-binding cassette sub-family A member 9; ABCA9
Swiss Prot
Q8IUA7
Reactivity
Human, Rat
Immunogen
A synthetic peptide corresponding to residues in Human ABCA9.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 163 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
ABCA9 polyclonal antibody detects endogenous levels of ABCA9 protein.
Applications Notes
Western blot (WB) analysis of ABCA9 polyclonal antibody at 1:500 dilution Line1:HEK293T whole cell lysate Line2:H9C2 whole cell lysate
Host or Source
Rabbit

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