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CGRRH polyclonal antibody

CAT: 0384-BS61283-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS61283-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CGR19 (Cell growth regulatory gene 19 protein), also known as Cell growth regulator with RING finger domain protein 1 and RING finger protein 197, is a 332 amino acid protein contains one RING-type zinc finger domain. CGR19 is ubiquitously expressed, with highest levels found in testis. It has been suggested that CGR19 plays a role in regulating the cell cycle because it inhibits growth in several cell lines. The gene encoding CGR19 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD) . The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder å1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Cell growth regulator with RING finger domain protein 1; Cell growth regulatory gene 19 protein; RING finger protein 197; CGRRF1; CGR19; RNF197
Swiss Prot
Q99675
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human CGRRH.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 38 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CGRRH polyclonal antibody detects endogenous levels of CGRRH protein.
Applications Notes
Western blot (WB) analysis of CGRRH polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:3T3 whole cell lysate Lane3:H9C2 whole cell lysate
Host or Source
Rabbit

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