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SPTBN5 polyclonal antibody

CAT: 0384-BS61279-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS61279-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Whole-exome sequencing (WES) identified 46 non-synonymous and 13 synonymous somatic single-nucleotide polymorphisms (SNPs) and one frameshift deletion in the coding regions. Specifically, mutations of CDKN2A, TP53, SPTBN5, NOTCH2, and FAM136A were found in the databases. Copy number aberration (CNA) analysis revealed that the cell line loses chromosome 3p and 9p, but lacks amplification of 3q and 11q (as does HPV-negative, smoking-unrelated OTSCC) . It also exhibits four distinctive focal amplifications in chromosome 19p, containing 131 genes without SNPs. Particularly, 52 genes showed >3- to 4-fold amplification and could be potential oncogenic drivers.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Spectrin beta chain, non-erythrocytic 5; Beta-V spectrin; SPTBN5; BSPECV; HUBSPECV; HUSPECV
Swiss Prot
Q9NRC6
Reactivity
Human
Immunogen
Synthetic peptide, corresponding Human SPTBN5.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 416 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
SPTBN5 pAb detects endogenous levels of SPTBN5 protein.
Applications Notes
Western blot (WB) analysis of SPTBN5 pAb at 1:500 dilution Lane1:HEK293T whole cell lysate (40ug) Lane2:SGC7901 whole cell lysate (40ug) Lane3:Panc1 whole cell lysate (40ug)
Host or Source
Rabbit

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