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APOL3 polyclonal antibody

CAT: 0384-BS61133-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS61133-01Size:50 µL
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Background
Apolipoproteins are protein components of plasma lipoproteins. The apolipoprotein L gene family encodes six highly homologous proteins designated apoL1-6, which are associated with large high density type lipoproteins (HDL) . The human apoL family maps to chromosome 22q12.1-13.1 within a 127,000 bp region. apoL2 and apoL3 may allow the binding of lipids to organelles or may be involved in the movement of lipids in the cytoplasm. apoL2 localizes to the cytoplasm and is widely expressed, with the highest levels observed in the lung, thymus, pancreas, placenta, adult brain and prostate. The apoL2 protein is also detected in the spleen, liver, kidney, colon, small intestine, uterus, spinal cord, adrenal gland, salivary gland, trachea, mammary gland, skeletal muscle, testis and fetal brain and liver. apoL3 also localizes to the cytoplasm and is widely expressed, with highest levels detected in the prostate, lung and placenta. It is also detected in kidney, bone marrow, spleen, thymus, spinal cord, adrenal gland, salivary gland, trachea and mammary gland. Lower levels of apoL3 are observed in the brain, heart, fetal liver, pancreas and testis.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Apolipoprotein L3; Apolipoprotein L-III; ApoL-III; TNF-inducible protein CG12-1; CG12_1
Swiss Prot
O95236
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human APOL3.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 36, 44kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
APOL3 polyclonal antibody detects endogenous levels of APOL3 protein.
Applications Notes
Western blot (WB) analysis of APOL3 polyclonal antibody at 1:500 dilution Line1:A549 whole cell lysate Line2:PC12 whole cell lysate Line3:sp20 whole cell lysate
Host or Source
Rabbit

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