INHBB polyclonal antibody

The TGFβ superfamilyis composed of numerous growth and differentiation factors, including transforming growth factor β (TGFβ) 1, 2 and 3; growth/ differentiation factor (GDF) 1 through 8; Mullerian inhibiting substance (MIS) ; bone morphogenic protein (BMP) 2 through 8; glialcell line-derived neurotrophic factor (GDNF) ; Inhibins (α, β-A, β-B and β-C), Lefty and Nodal. Members of the TGFβ superfamily are involved in embryonic development and adult tissue homeostasis. Inhibins and activinsinhibit and activate, respectively, the secretion of follitropin bythe pituitary gland. Inhibins and activins are involved in regulating a number of functions such as hypothala mic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, Insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. activins oppose the funtions of Inhibins. Inhibins are predominantly expressed in liver, uterus and ovarytissue. Inhibin A, a dimer ofαand β-A, and Inhibin B, a dimer of α and β-B, have been shown to inhibit the secretion of follicle stimulating hormone. Inhibin β-C forms a homodimer and its expression is predominant in adult liver.

9007-83-4

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Inhibin beta B chain; Activin beta-B chain; INHBB

P09529

Human, Mouse, Rat

A synthetic peptide corresponding to residues in Human INHBB.

Unconjugated

WB

WB: 1:500~1:1000

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Unmodification

~ 45 kDa

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.

INHBB polyclonal antibody detects endogenous levels of INHBB protein.

Western blot (WB) analysis of INHBB polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:H9C2 whole cell lysate