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ARHGAP30 polyclonal antibody

CAT: 0384-BS60757-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS60757-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins, resulting in downregulation of their active form. ARHGAP30 (Rho GTPase activating protein 30), also known as Rho-type GTPase-activating protein 30, is a 1,101 amino acid protein that contains one Rho-GAP domain and exists as four alternatively spliced isoforms. Conserved in chimpanzee, dog, cow, mouse and rat, ARHGAP30 is among the most neurite-enriched GAPs, which also includes ARHGAP21, FNBP2 and Bcr) . One of four single-nucleotide polymorphisms (SNPs) at the USF-1 gene locus, rs2774279, which is located in the promoter area of the USF-1 gene, which is in turn located within its flanking gene ARHGAP30, is linked to low-density lipoprotein cholesterol levels, incident type 2 diabetes mellitus and increased cardiovascular risk.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Rho GTPase-activating protein 30; Rho-type GTPase-activating protein 30; ARHGAP30
Swiss Prot
Q7Z6I6
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human ARHGAP30
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 119 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
ARHGAP30 polyclonal antibody detects endogenous levels of ARHGAP30 protein.
Applications Notes
Western blot (WB) analysis of ARHGAP30 polyclonal antibody at 1:500 dilution Lane1:MCF-7 whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:PC12 whole cell lysate
Host or Source
Rabbit

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