Products for Research Use Only
RegisterLogin

GFI1B polyclonal antibody

CAT: 0384-BS60592-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0384-BS60592-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Growth factor independent 1 (Gfi-1) is a transcriptional repressor that spe-cifically binds to the DNA consensus sequence TAAATCAC (A/T) GCA. The carboxy-terminus of Gfi-1 contains six C2H2-type zinc finger motifs, and zinc fingers 3, 4 and 5 are required for the binding of Gfi-1 to its DNA binding site. Gfi-1 also contains a 20 amino acid SNAG domain which mediates transcriptional repression. It represses Bax at the mRNA and protein levels, resulting in the inhibition of cell death. Gfi-1 is expressed outside the lymphoid system in granulocytes and activated macrophages. Gfi-1B, a related protein, is a transciptional repressor primarily expressed in bone marrow and spleen. Gfi-1B is a direct repressor of the p21 promoter and the SOCS-1 and -3 promoters. The genes encoding human Gfi-1 and Gfi-1B map to chromosome 1p22 and 9q34.13, respectively.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Zinc finger protein Gfi-1b; Growth factor independent protein 1B; Potential regulator of CDKN1A translocated in CML; GFI1B
Swiss Prot
Q5VTD8
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human GFI1B
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 37 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
GFI1B polyclonal antibody detects endogenous levels of GFI1B protein.
Applications Notes
Western blot (WB) analysis of GFI1B polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:sp2/0 whole cell lysate Lane3:H9C2 whole cell lysate
Host or Source
Rabbit

Related Products

CatalogName
BS65757-01GFI1 Polyclonal Antibody
BS76978GFI1 polyclonal antibody
BZ16794-01Polyclonal antibodyPN1 polyclonal antibody
BS75206-01AaaaaASPH polyclonal antibody
BS5662-01CHST1 polyclonal antibody
BS71123-01COPS7A polyclonal antibody
BS65479-01GDN Polyclonal Antibody
BS8691-01TUSC2 polyclonal antibody
BS72779-01FBLIM1 polyclonal antibody
BZ16836APE1 polyclonal antibody

Alternative Products

CatalogName
RD217998A-01GFI1B Polyclonal Antibody
35-1832-50Polyclonal Antibody to GFI1b
ARO-A21604-01Anti-GFI1B Polyclonal Antibody
NBP3-03957-20ulRabbit Polyclonal GFI1B Antibody
TA372615GFI1B Rabbit Polyclonal Antibody
H00008328-B01PMouse Polyclonal GFI1B Antibody

Popular Products