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RLN3 polyclonal antibody

CAT: 0384-BS60503-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS60503-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Relaxin 3 is part of the Relaxin-like peptide family that plays an important neuropeptide signaling role. Relaxin 3 is a ligand for two structurally related G protein-coupled receptors, human Relaxin receptor 3 and Relaxin receptor 4. The greatest levels of Relaxin 3 expression occur in the brain, specifically in the pons/medulla, with highest levels in the pars ventromedialis of the dorsal tegmental nucleus and with lower levels in the hippocampus and olfactory regions. Significant expression is also observed in the spleen, thymus, lung and ovary. Relaxin 3 inhibits Forskolin-stimulated cAMP accumulation in a dose-dependent manner in cells that express Relaxin receptor 3. Acute and repeated administration of Relaxin 3 causes a decrease in levels of the plasma thyroid stimulating hormone, suggesting that Relaxin 3 may play a role in long-term control of food intake.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Relaxin-3; Insulin-like peptide INSL7; Insulin-like peptide 7; Prorelaxin H3; RLN3; INSL7, RXN3, ZINS4; UNQ6188; PRO20213
Swiss Prot
Q8WXF3
Reactivity
Human, Mouse
Immunogen
A synthetic peptide corresponding to residues in Human RLN3.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 15 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
RLN3 polyclonal antibody detects endogenous levels of RLN3 protein.
Applications Notes
Western blot (WB) analysis of RLN3 polyclonal antibody at 1:500 dilution Lane1:Hela whole cell lysate Lane2:HEK293T whole cell lysate Lane3:Raw264.7 whole cell lysate
Host or Source
Rabbit

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