IGFL2 polyclonal antibody

CAT: 0384-BS60493-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS60493-01Size:50 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
The insulin gene family, comprised of insulin, relaxin and insulin-like growth factors I and II (IGF-I and IGF-II), represents a group of structurally related polypeptides whose biological functions have diverged. The IGFs, or somato-medins, constitute a class of polypeptides that have a key role in pre-adolescent mammalian growth. IGF-I and -II are critical regulators of cell proliferation and differentiation. Most of the growth promoting properties of both ligands are mediated by the IGF-I receptor (IGF-IR) . IGF- I and -II, respectively known as somatomedin C and somatomedin A, are single chain polypeptides which share an amino acid sequence homology of about 47% with insulin. IGF-I expression is regulated by growth hormone and mediates postnatal growth, while IGF-II is induced by placental lactogen during prenatal development. IGF-II is a fetal growth factor, influenced by placental lactogen and abundantly expressed by placental trophoblasts. IGF-II and IGF-binding protein 1 (IGFBP1) gene variants are associated with overfeeding-induced metabolic changes. The human IGF-II gene maps to chromosome 11p15.5, encoding a 180 amino acid protein which is the precursor to IGF-II.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Insulin growth factor-like family member 2; IGFL2
Swiss Prot
Q6UWQ7
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human IGFL2.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 13 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IGFL2 polyclonal antibody detects endogenous levels of IGFL2 protein.
Applications Notes
Western blot (WB) analysis of IGFL2 polyclonal antibody at 1:500 dilution Lane1:NIH-3T3 whole cell lysate Lane2:H9C2 whole cell lysate Lane3:Jurkat whole cell lysate
Host or Source
Rabbit

Related Products

CatalogName
BS78835-01IGFL3 polyclonal antibody
BS6632-01IGF2 polyclonal antibody
BS90688IGF2 polyclonal antibody
BS79873IGF2 polyclonal antibody
BZ16794-01Polyclonal antibodyPN1 polyclonal antibody
MB66160-01IGF2 monoclonal antibody
MB66134IGF2 monoclonal antibody
BS75576PTS polyclonal antibody
BS77565-01PDLIM7 polyclonal antibody
BS78796-01ABCA3 polyclonal antibody

Alternative Products

CatalogName
MBS8531117-01IGFL2 Polyclonal Antibody
TMAB-07561-01Anti-IGFL2 Polyclonal Antibody
NBP3-09570-100ulRabbit Polyclonal IGFL2 Antibody
TA332341IGFL2 Rabbit Polyclonal Antibody
PAV1845Rabbit Anti-IGFL2 Polyclonal Antibody
MBS8513387-01IGFL2 Antibody
A16164Anti-IGFL2 Antibody
C44519IGFL2 Conjugated Antibody
483398IGFL2

Popular Products