COX7B polyclonal antibody

CAT: 0384-BS60476-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS60476-01Size:50 µL
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Background
The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water and ATP. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. COX7b (cytochrome c oxidase subunit VIIb polypeptide) and COX7b2 (cytochrome c oxidase subunit VIIb polypeptide 2) are 80 and 81 amino acid proteins, respectively, which exist as components of the COX complex, therefore playing an important role in electron transport. A rare polymorphism in the COX7b2 gene at codon 26 may be linked to nasopharyngeal carcinoma (NPC), the most common head and neck cancer in southern China.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Cytochrome c oxidase subunit 7B, mitochondrial; Cytochrome c oxidase polypeptide VIIb; COX7B
Swiss Prot
P24311
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in HumanCOX7B.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 9 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
COX7B polyclonal antibody detects endogenous levels of COX7B protein.
Applications Notes
Western blot (WB) analysis of COX7B polyclonal antibody at 1:500 dilution Lane1:RAW264.7 whole cell lysate Lane2:H9C2 whole cell lysate Lane3:HELA whole cell lysate
Host or Source
Rabbit

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