RegisterLogin

BIRC2 polyclonal antibody

CAT: 0384-BS60459-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS60459-01Size:50 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Three mammalian homologs of baculovirus p35, designated MIHA (mammalian IAP homolog A), MIHB and MIHC have been described. These three mammalian inhibitor of apoptosis proteins (IAPs) are designated XIAP, c-IAP1 and c-IAP2, respectively. XIAP, c-IAP1 and c-IAP2 share an N-terminal baculovirus IAP repeat (BIR) motif and a C-terminal RING finger. Although c-IAP1 and c-IAP2 do not directly associate with the TNF receptor (TNF-R), they efficiently block TNF-mediated apoptosis through their interaction with the downstream TNF-R effectors, TRAF1 and TRAF2. The interaction between the TRAF1/TRAF2 heterocomplexes and c-IAPs is dependent on a functional BIR motif.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Baculoviral IAP repeat-containing protein 2; C-IAP1; IAP homolog B; Inhibitor of apoptosis protein 2; IAP-2; hIAP-2; hIAP2; RING finger protein 48; TNFR2-TRAF-signaling complex protein 2; API1; IAP2; MIHB; RNF48
Swiss Prot
Q13490
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human BIRC2.
Conjugation
Unconjugated
Related Pathways
Regulation of Apoptosis, Necrotic Cell Death, Death Receptor Signaling
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 70 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
BIRC2 polyclonal antibody detects endogenous levels of BIRC2 protein.
Applications Notes
Western blot (WB) analysis of BIRC2 polyclonal antibody at 1:500 dilution Lane1:Jurkat cell lysate Lane2:sp2/0 cell lysate Lane3:PC12 cell lysate
Host or Source
Rabbit

Related Products

CatalogName
MB0128-01BIRC2 monoclonal antibody
PPL01846-2aPcDNA3.1 (+) -Flag-BIRC2
BS78678BIRC7 polyclonal antibody
BS8491-01BIRC7 polyclonal antibody
MB0129BIRC3 monoclonal antibody
BZ16794-01Polyclonal antibodyPN1 polyclonal antibody
BS60703-01LILRB polyclonal antibody
BS66191-01FEZ1 polyclonal antibody
BS66193-01LIAS polyclonal antibody
BS66202-01SLC31A1 polyclonal antibody

Alternative Products

CatalogName
MBS8532367-01BIRC2 Polyclonal Antibody
HC658024-01Anti-BIRC2 Polyclonal Antibody
E10G07637BIRC2 Rabbit Polyclonal Antibody

Popular Products