Stat5b polyclonal antibody

CAT: 0384-BS6031-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS6031-01Size:50 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Stat5a and Stat5b (signal transducer and activator of transcription 5a and 5b; 96% homology) undergo receptor tyrosine kinase or G protein-coupled receptor-dependent phosphorylation in response to cytokines or growth factors, and then form homo- or heterodimers that translocate to the nucleus where they initiate transcription. Activation of Stat5b via IL-2, IL-4, CSF1 and growth hormones influences TCR signaling, apoptosis, adult mammary gland development and sexual dimorphism of liver gene expression. Stat5b is the major liver-expressed Stat5 form that has been shown to fuse with retinoic acid receptor-α gene in acute promyelocytic leukemias (APLL) .
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Signal transducer and activator of transcription 5B; STA5B; STAT5; Stat5b; Transcription factor STAT5B
Swiss Prot
P51692
Reactivity
Human, Rat
Immunogen
Recombinant full length Human Stat5b.
Conjugation
Unconjugated
Related Pathways
Immune Cell Signaling, Jak Stat : IL-6 Receptor Signaling
Applications
WB IF
Dilution
WB: 1:500~1:2000 IF: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 90 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
STAT5B polyclonal antibody detects endogenous levels of STAT5B protein.
Applications Notes
WesternBlot (WB) analysis of STAT5B polyclonal antibody in extracts from K562, PC12, MCF7 and HepG2 cells.
Host or Source
Rabbit

Related Products

CatalogName
MB11639STAT5b monoclonal antibody
MB12260STAT5b monoclonal antibody
PPL00566-1aPET28a-STAT5B
MB66458STAT5B Rabbit monoclonal antibody
PPL00566PCMV-SPORT6-STAT5B
PPL00566-2aPCMV-Flag-STAT5B
BS45189-01STAT5b Recombinant Rabbit mAb
PPL00566-2cPcDNA3.1-Flag-STAT5B
PPL00566-2bPCMV-HA-Flag-STAT5B
PPL00566-3aPPLK/GFP+Puro-STAT5B shRNA-1

Alternative Products

CatalogName
MBS125523-01STAT5B Polyclonal Antibody

Popular Products