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IFN-ω polyclonal antibody

CAT: 0384-BS60296-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS60296-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The genes encoding type I interferons (IFNs), which include 14 IFN-α genes, 1 IFN-β gene, 1 IFN-ω (also known as IFN-α II1) gene, and a number of IFN-ω pseudogenes, are clustered on human chromosome 9. Interferons-α and -β are cytokines that are widely known to induce potent anti-viral activity. IFN-α and -β exert a variety of other biological effects, including anti-tumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. IFN-ω is antigenically different from human IFN-α, IFN-β or IFN-γ, but is a component of natural mixtures of IFN species produced by virus-induced leukocytes or Burkitt's lymphoma cells. The Type I interferon receptor (IFN-αR) interacts with IFN-α, IFN-β and IFN-ω, and seems to be a multisubunit receptor.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Interferon omega-1; Interferon alpha-II-1; IFNW1
Swiss Prot
P05000
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human IFN-ω.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 20 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IFN-ω polyclonal antibody detects endogenous levels of IFN-ω protein.
Applications Notes
Western blot (WB) analysis of IFN-ω polyclonal antibody at 1:500 dilution Lane1:HEK293T cell lysate Lane2:NIH-3T3 cell lysate Lane3:H9C2 cell lysate
Host or Source
Rabbit

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