FXYD2 polyclonal antibody

CAT: 0384-BS60253-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS60253-01Size:50 µL
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Background
The human FXYD2 (pronounced fix-id) gene maps to chromosome 11q23 and encodes the gamma subunit of Na/K-ATPase (NKA) . FXYD2 ? subunit modulates NKA activity by inducing ion channel activity. The mammalian FXYD family maintains Na+ and K+ gradients between the intracellular and extracellular milieus of cells in processes such as renal Na+-reabsorption, muscle contraction and neuronal excitability. FXYDs are single-span membrane proteins that share a 35 amino acid signature domain, beginning with the sequence PFXYD and containing 7 invariant and 6 conserved amino acids. Other members of the FXYD family include FXYD1 (PLM, phospholemman), FXYD3 (Mat8, mammary tumor protein 8), FXYD4 (CHIF) and FXYD5 (RIC) .
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Sodium/potassium-transporting ATPase subunit gamma; Na (+) /K (+) ATPase subunit gamma; FXYD domain-containing ion transport; regulator 2; Sodium pump gamma chai; FXYD2; ATP1C, ATP1G1
Swiss Prot
P54710
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human FXYD2.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 7 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
FXYD2 polyclonal antibody detects endogenous levels of FXYD2 protein.
Applications Notes
Western blot (WB) analysis of FXYD2 polyclonal antibody at 1:500 dilution Lane1:HepG2 whole cell lysate Lane2:Mouse lung tissue lysate Lane3:Rat brain tissue lysate
Host or Source
Rabbit

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