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HOX-C12 polyclonal antibody

CAT: 0384-BS60164-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS60164-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The Homeobox (Hox) proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. In mammals, there are four gene clusters encoding Hox proteins, namely HoxA, HoxB, HoxC and HoxD, that are located on different chromosomes, each consisting of 9-11 tandemly arranged genes. HoxC12 (Homeobox C12), also known as Hox3, Hox3F or HOC3F, is a member of the Abd-B homeobox (Hox) family and is encoded by a gene from the HoxC cluster. HoxC12 is a 282 amino acid long nuclear protein that contains one homeobox DNA-binding domain.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Homeobox protein Hox-C12; Homeobox protein Hox-3F; HOXC12; HOC3F; HOX3F
Swiss Prot
P31275
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human HOX-C12.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 30 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
HOX-C12 polyclonal antibody detects endogenous levels of HOX-C12 protein.
Applications Notes
Western blot (WB) analysis of HOX-C12 polyclonal antibody at 1:500 dilution Lane1:MCF-7 whole cell lysate Lane2:NIH-3T3 whole cell lysate Lane3:PC12 whole cell lysate
Host or Source
Rabbit

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