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CIB4 polyclonal antibody

CAT: 0384-BS60122-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS60122-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CIB4 (calciumand integrin-binding familymember 4) is a 185 amino acid protein thatcontainsthree EF-hand domains. CIB4 is closelyrelated to CIB (CIB has one less EF-hand domain), which isknown to bind to IntegrinαIIβ in platelets and isinvolved in signal transduction. The gene encoding CIB4mapsto human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare andmorbid skin deformity, is associatedwithmutationsin the ABCA12 gene, while the lipidmetabolic disordersitosterolemia is associated with defectsin the ABCG5 and ABCG8 genes. Additionally, an extremelyrare recessive genetic disorder, Alströmsyndrome, iscaused bymutationsin the ALMS1 gene, whichmaps to chromosome 2.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Calcium and integrin-binding family member 4; CIB4
Swiss Prot
A0PJX0
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human CIB4.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 22 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CIB4 polyclonal antibody detects endogenous levels of CIB4 protein.
Applications Notes
Western blot (WB) analysis of CIB4 polyclonal antibody at 1:500 dilution Lane1:HepG2 whole cell lysate Lane2:Mouse kidney tissue lysate Lane3:Rat liver tissue lysate
Host or Source
Rabbit

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