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ANP32C polyclonal antibody

CAT: 0384-BS5864-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS5864-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ANP32C (acidic (leucine-rich) nuclear phosphoprotein 32 family, member C), also known as PP32R1 (phosphoprotein 32-related protein 1) or tumorigenic protein pp32r1, is a 234 amino acid protein that contains 4 leucine-rich repeats and belongs to the ANP32 family. ANP32C shares 87.7% amino acid sequence identity with ANP32A, a tumor suppressor that inhibits a variety of cancers, such as prostate and breast cancers. Although similar to ANP32A, ANP32C is tumorigenic and is expressed in activated stem cells, such as mobilized CD34+ cells and cord blood CD34+ cells, but not in resting bone marrow CD34+ cells. ANP32C is also expressed in a variety of neoplastic cell lines, mainly in prostatic adenocarcinoma cell lines, but not in normal protastic tissue, and may also modulate the oncogenic potential of human prostate cancer.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Acidic leucine-rich nuclear phosphoprotein 32 family member C; Phosphoprotein 32-related protein 1; Tumorigenic protein pp32r1; PP32R1
Swiss Prot
O43423
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 161-206 of Human ANP32C.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 27 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
ANP32C polyclonal antibody detects endogenous levels of ANP32C protein.
Applications Notes
Western blot (WB) analysis of ANP32C polyclonal antibody at 1:500 dilution Lane1:Hela cell lysate Lane2:sp2/0 cell lysate Lane3:H9C2 cell lysate
Host or Source
Rabbit

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