DRD1 polyclonal antibody

CAT: 0384-BS5692-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS5692-01Size:50 µL
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Background
The members of the G protein coupled receptor family are distinguished by their slow transmitting response to ligand binding. These transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. ß-adrenergic receptor binds to adrenaline activates adenylyl cyclase, while α2-adrenergic receptor binds to adrenaline inhibits adenylyl cyclase. The dopamine receptors are divided into two classes, D1 and D2, which differ in their functional characteristics in that D1 receptors stimulate adenylyl cyclase while D2 receptors inhibit adenylyl cyclase activity. Five different subtypes of dopamine receptor have been described to date. D1DR and D5DR belong to the D1 subclass, while D2DR, D3DR and D4DR belong to the D2 subclass.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
D (1A) dopamine receptor; Dopamine D1 receptor; D1DR
Swiss Prot
P21728
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to the 187-232 of Human DRD1.
Conjugation
Unconjugated
Applications
WB IF
Dilution
WB: 1:500~1:1000 IF: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 49 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
DRD1 polyclonal antibody detects endogenous levels of DRD1 protein.
Applications Notes
Western blot (WB) analysis of DRD1 polyclonal antibody at 1:500 dilution Lane1:Hela cell lysate Lane2:NIH-3T3 cell lysate Lane3:H9C2 cell lysate
Host or Source
Rabbit

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