SARNP polyclonal antibody

• Background:

  SARNP (SAP domain-containing ribonucleoprotein), also known as CIP29 (Cytokine-induced protein of 29 kDa) and HCC1 (Nuclear protein Hcc-1), is a 210 amino acid nuclear protein whose expression is upregulated by erythropoietin. Induction of SARNP expression is associated with cell cycle progression and apoptosis. This transcription factor binds both single stranded (ss) and double stranded (ds) DNA, though it has higher affinity for ssDNA. SARNP is expressed at low levels in pancreas, spleen, testis, liver, kidney, heart and thymus, and is found to be expressed at higher levels in pancreatic adenocarcinoma and hepatocellular carcinoma.

• Structure Composition:

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  SAP domain-containing ribonucleoprotein; Cytokine-induced protein of 29 kDa; Nuclear protein Hcc-1; Proliferation-associated cytokine-inducible protein CIP29; Synonyms: HCC1; ORF Names: HSPC316

• Swiss Prot:

  P82979

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic peptide, corresponding to amino acids 165-210 of Human SARNP.

• Conjugation:

  Unconjugated

• Applications:

  WB ICC

• Dilution:

  WB: 1:500~1:1000 ICC: 1:50~1:200

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodification

• Molecular Weight:

  ~ 29 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  SARNP polyclonal antibody detects endogenous levels of SARNP protein.

• Applications Notes:

  Western blot (WB) analysis of SARNP polyclonal antibody at 1:500 dilution Lane1:Jurkat cell lysate Lane2:Mouse heart tissue lysate Lane3:Rat liver tissue lysate

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4