LY75 polyclonal antibody

CAT: 0384-BS5653-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS5653-01Size:50 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
DEC-205 (LY75, lymphocyte antigen 75, GP200-MR6) is a 1,695 residue (mature form) multilectin receptor that belongs to the MMR (macrophage mannose receptor) family of multidomain molecules. MMR family molecules mediate membrane receptor targeting to endosomes or lysosomes rich in major histocompatibility complex class II (MHC II) products. Expressed in mature dendritic cells (DC), DEC-205 contains an extracellular N-terminal cysteine-rich domain, a fibronectin type II domain, ten C-type carbohydrate recognition domains, a single transmembrane region and a small cytoplasmic C-terminal domain (31 amino acids) containing a tyrosine at 1679. DEC-205 elicits either an agonistic or antagonistic effect on IL-4 function, which is demonstrated by the ability of DEC-205 to imitate IL-4-induced maturation of epithelium or to inhibit IL-4-induced proliferation of T cells, respectively.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Lymphocyte antigen 75; Ly-75; C-type lectin domain family 13 member B; DEC-205; gp200-MR6; CD205; CLEC13B; DEC205
Swiss Prot
O60449
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 509-554 of Human LY75.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 198 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
LY75 polyclonal antibody detects endogenous levels of LY75 protein.
Applications Notes
Western blot (WB) analysis of LY75 polyclonal antibody at 1:500 dilution Lane1:MCF-7 cell lysate Lane2:sp2/0 cell lysate Lane3:H9C2 cell lysate
Host or Source
Rabbit

Related Products

CatalogName
BS40859LY75 Rabbit monoclonal antibody
BZ16794-01Polyclonal antibodyPN1 polyclonal antibody
BS78737-01GAB1 polyclonal antibody
BS71460-01CRYGC polyclonal antibody
BS7323-01GPX4 polyclonal antibody
BS74856-01COX6B1 polyclonal antibody
BS62420-01ZDHHC15 polyclonal antibody
BS67453Paxillin polyclonal antibody
BS8586-01HOXB7 polyclonal antibody
BS71092-01LAMB3 polyclonal antibody

Alternative Products

CatalogName
AP26335PU-NLY75 (LY75-CD302) Chicken Polyclonal Antibody
TA316488LY75 (LY75-CD302) Rabbit Polyclonal Antibody
RD87147A-01LY75 Polyclonal Antibody
ANT-10919-100ugCD205 / LY75 Polyclonal Antibody
E53P11061LY75 Rabbit Polyclonal Antibody
E55A03068CD205/LY75 Polyclonal Antibody
A57440-050Ly75 Polyclonal Antibody, Biotin Conjugated
A57438-050Ly75 Polyclonal Antibody, HRP Conjugated
A57439-050Ly75 Polyclonal Antibody, FITC Conjugated
CAU25659-01Lymphocyte Antigen 75 (LY75) Polyclonal Antibody

Popular Products