ARSE polyclonal antibody

• Background :

  Arylsulfatase E, also known as CDPX, CDPX1 or CDPXR, is a 589 amino acid Golgi apparatus protein expressed in the pancreas, liver and kidney. Belonging to the sulfatase family, Arylsulfatase E may be essential for the correct composition of cartilage and bone matrix during development. Inhibited by warfarin, Arylsulfatase E activity occurs under optimal pH and temperature. Defects in the gene encoding Arylsulfatase E are the cause of chondrodysplasia punctata X-linked recessive type 1 (CDPX1), which is characterized by aberrant bone mineralization, severe underdevelopment of nasal cartilage and distal phalangeal hypoplasia. Arylsulfatase E has no activity toward steroid sulfates.

• Structure Composition :

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative :

  Arylsulfatase E; ASE; ARSE

• Swiss Prot :

  P51690

• Reactivity :

  Human

• Immunogen :

  Synthetic peptide, corresponding to amino acids 208-253 of Human ARSE.

• Conjugation :

  Unconjugated

• Applications :

  WB ICC

• Dilution :

  WB: 1:500~1:1000 ICC: 1:50~1:200

• Purity :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification :

  Unmodification

• Molecular Weight :

  ~ 66 kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  ARSE polyclonal antibody detects endogenous levels of ARSE protein.

• Applications Notes :

  Western blot (WB) analysis of ARSE polyclonal antibody at 1:500 dilution Lane1:Hela cell lysate Lane2:HEK293T cell lysate

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4