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CPM (L113) polyclonal antibody

CAT: 0384-BS3827-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS3827-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Carboxypeptidase M (CPM) is a 443 amino acid protein belonging to the metallo-carboxypeptidase (metallo-CP) family. Localized to the cell membrane, CPM contains hydrophobic regions in the N and C- termini and has six potential asparagine-linked glycosylation sites. Functionally, CPM specifically removes C-terminal basic amino acids (arginine or lysine) from proteins and polypeptides and is believed to play a role in monocyte to macrophage differentiation. CPM is also thought to play an important role in the control of peptide hormone and growth factor activity at the cell surface, as well as in the membrane-localized degradation of extracellular proteins. Three isoforms of this protein exist as a result of alternative splicing events.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Carboxypeptidase M; CBPM; CPM; Renal carboxypeptidase; Urinary carboxypeptidase B
Swiss Prot
P14384
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 80-130 of Human CPM.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 51 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CPM (L113) polyclonal antibody detects endogenous levels of CPM protein.
Applications Notes
Western blot (WB) analysis of CPM (L113) pAb at 1:500 dilution Lane1:Hela whole cell lysate (40ug) Lane2:The Uterus tissue lysate of Mouse (40ug) Lane3:The Uterus tissue lysate of Rat (40ug)
Host or Source
Rabbit

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