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NPY (P94) polyclonal antibody

CAT: 0384-BS3551-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS3551-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
NPY (neuropeptide Y) is a 36 amino acid protein that consists of a polyproline stretch followed by an amphipathic a-helix. NPY shares a 50% amino acid homology with pancreatic polypeptide gene (PP) . NPY is expressed throughout the central and peripheral nervous system, particularly in the deep layers of the cortex and smaller cell bodies in the white matter. NPY interacts with the Y-receptor family of G protein-coupled receptors. NPY interacts with NPY receptor Y1 to increase corticotropin levels and decrease noradrenaline levels in the hypothalamus. Through interactions in the hypothalus, NPY plays important roles in the regulation of energy balance by stimulating food intake. NPY favors energy storage by increasing lipoprotein lipase activity in white adipose tissue.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Pro-neuropeptide Y; Neuropeptide Y; Neuropeptide tyrosine; NPY; C-flanking peptide of NPY; CPON; NPY
Swiss Prot
P01303
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 61-110 of Human NPY.
Conjugation
Unconjugated
Related Pathways
Neuronal and Glial Cell Marker Atlas
Applications
IHC
Dilution
IHC:1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 11 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
NPY (P94) polyclonal antibody detects endogenous levels of NPY protein.
Host or Source
Rabbit

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