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NOC2L (I634) polyclonal antibody

CAT: 0384-BS3150-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS3150-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GADD 153, a growth arrest and DNA damage-inducible gene, encodes a C/EBP-related nuclear protein. This protein has also been designated C/EBP-homologous protein (CHOP-10 or C/EBP zeta) . GADD 153 expression is induced by a variety of cellular stresses, inducing nutrient deprivation and metabolic perturbations. GADD 153 functions to block cells in G1 to S phase during cell cycle progression and acts by dimerizing with other C/EBP proteins to direct GADD 153 dimers away from “classical” C/EBP binding sites, recognizing instead unique “nonclassical” sites. Thus, GADD 153 acts as a negative modulator of C/EBP-like proteins in certain terminally differentiated cells. GADD 153 belongs to the CBF/MAK21 family, which also includes NOC2L, NOC3L and NOC4L. NOC2L is a 749 amino acid nuclear protein that may play a role in cell cycle regulation.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Nucleolar complex protein 2 homolog; Protein NOC2 homolog; NOC2-like protein; Novel INHAT repressor; NOC2L; NIR
Swiss Prot
Q9Y3T9
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 602-650 of Human NOC2L.
Conjugation
Unconjugated
Applications
IHC
Dilution
IHC:1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 85 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
NOC2L (I634) polyclonal antibody detects endogenous levels of NOC2L protein
Host or Source
Rabbit

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