Products for Research Use Only

BRCAA1 (D810) polyclonal antibody

CAT: 0384-BS2935-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS2935-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The breast cancer-associated antigen BRCAA1, also designated ARID domaincontaining protein 4B (ARID4B), Sin3-associated polypeptide p180 (SAP180), or Retinoblastoma-binding protein 1-like 1 (RBBP1L1 or RBP1L1), shares 37% amino acid identity and an identical antigen epitope, SSKKQKRSHK, with Rb binding protein 1. High expression of BRCAA1 mRNA has been found in human breast, lung, colon, pancreatic and ovarian cancers, as well as in normal testis. This expression pattern indicates that BRCAA1 can be uses as a molecular marker for a broad range of human malignancies. BRCAA1 also interacts with RBBP1/ARID4A and regulates genomic imprinting at the Prader-WIlli syndrome (PWS) /Angelman syndrome (AS) domain.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
AT-rich interactive domain-containing protein 4B; ARID domain-containing protein 4B; 180 kDa Sin3-associated polypeptide; Sin3-associated polypeptide p180; Breast cancer-associated antigen BRCAA1; Histone deacetylase complex subunit SAP180; Retinoblastoma-binding protein 1-like 1; ARID4B; BRCAA1; RBBP1L1; RBP1L1; SAP180
Swiss Prot
Q4LE39
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 776-832 of Human BRCAA1.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 150 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
BRCAA1 (D810) polyclonal antibody detects endogenous levels of BRCAA1 protein.
Applications Notes
Western blot (WB) analysis of BRCAA1 (D810) pAb at 1:500 dilution Lane1:Hela whole cell lysate (40ug) Lane2:A2780 whole cell lysate (40ug) Lane3:SK-OVCAR3 whole cell lysate (40ug) Lane4:H9C2 whole cell lysate (40ug)
Host or Source
Rabbit