EphA7 (E477) polyclonal antibody

CAT: 0384-BS2067-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS2067-01Size:50 µL
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Background
EphAs are a family of receptor tyrosine kinases that are involved in axonal guidance during development. These receptors and their ligands, the ephrins, act via repulsive mechanisms to guide growing axons towards their appropriate targets and allow for the correct developmental connections to be made. Ligand binding to an Eph receptor results in tyrosine phosphorylation of the kinase domain, and repulsion of axonal growth cones and migrating cells.Three different EphA7 splice variants, a full-length form and two truncated versions lacking kinase domains, are expressed in the neural folds.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Ephrin type-A receptor 7; Tyrosine-protein kinase receptor EHK-3; Eph-homology kinase-3; Receptor protein-tyrosine kinase HEK11
Swiss Prot
Q15375
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 443-495 of Human EphA7.
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB: 1:500~1:1000 IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 112 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
EphA7 (E477) polyclonal antibody detects endogenous levels of EphA7 protein.
Applications Notes
Western blot (WB) analysis of EphA7 (E477) pAb at 1:500 dilution Lane1:3T3-L1 whole cell lysate (40ug) Lane2:H9C2 whole cell lysate (40ug) Lane3:A549 whole cell lysate (40ug) Lane4:HEK293T whole cell lysate (40ug)
Host or Source
Rabbit

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