AR-β2 (L342) polyclonal antibody

CAT: 0384-BS1716-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS1716-01Size:50 µL
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Background
Beta 2 Adrenergic Receptor is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca (V) 1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene contains no introns in either its coding or untranslated sequences. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. Expression of the beta 2 Adrenergic Receptor has been reported in adipose, blood, brain, heart, lung, nose, pancreas, skeletal muscle, skin, and vessel.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
ADRB2; ADRB2R; ADRBR; B2AR; BAR; BETA2AR; Beta-2 adrenergic receptor; ARβ2
Swiss Prot
P07550
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 311-360 of Human AR-β2.
Conjugation
Unconjugated
Applications
IHC IF
Dilution
IHC: 1:50~1:200 IF: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 47 kDa, 68 kDa (glycosylated), 95 kDa (Dimer)
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
AR-β2 (L342) polyclonal antibody detects endogenous levels of AR-β2 protein.
Host or Source
Rabbit

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