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ATP6 polyclonal antibody

CAT: 0384-BS1681-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS1681-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ATP6, also known as MT-ATP6, ATPASE6 or MTATP6, is a 226 amino acidmulti-passmembrane protein that localizestomitochondria and functions as a component of the F0 proton channel, playing a direct role in the transport of protons acrossthe mitochondrial membrane. Defectsin the gene encoding ATP6 are the cause of infantile bilateralstriatal necrosis, Leigh syndrome (LS), Leber hereditary optic neuropathy (LHON) and neurogenic muscle weakness, ataxia, and retinitis pigmentosa (NARP), all of which are neurological or retinal disorders. The gene encoding ATP6 exists as part of themitochondrial genome.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
ATP synthase subunit a; F-ATPase protein 6; Mtatp6; Atp6; Atpase6; mt-Atp6
Swiss Prot
P00848
Reactivity
Mouse, Rat
Immunogen
A synthetic peptide corresponding to amino acids 55-70 of Mouse ATP6.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000 IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 25 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
ATP6 polyclonal antibody detects endogenous levels of ATP6 protein.
Applications Notes
Western blot (WB) analysis of ATP6 polyclonal antibody at 1:1000 dilution Lane1:The muscle tissue lysate of Rat (47μg) Lane2:The muscle tissue lysate of Mouse (37μg)
Host or Source
Rabbit

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