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TRADD (L282) polyclonal antibody

CAT: 0384-BS1480-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS1480-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TRADD (TNF R1 associated death domain) is a 34kDa protein that associates with the death domains of both FAS and TNFR1 via their DDH regions. Over expression of TRADD leads to NFkB activation and apoptosis in the absence of TNF.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Tumor necrosis factor receptor type 1-associated DEATH domain protein; TNFR1-associated DEATH domain protein; TNFRSF1A-associated via death domain; TRADD
Swiss Prot
Q15628
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 250-304 of Human TRADD.
Conjugation
Unconjugated
Related Pathways
Death Receptor Signaling
Applications
WB IHC
Dilution
WB: 1:500~1:1000 IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 34 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
TRADD (L282) polyclonal antibody detects endogenous levels of TRADD protein.
Applications Notes
Western blot (WB) analysis of TRADD (L282) pAb at 1:500 dilution Lane1:PC12 whole cell lysate (20ug) Lane2:AML-12 whole cell lysate (20ug) Lane3:MCF-7 whole cell lysate (40ug) Lane4:HEK293T whole cell lysate (40ug) Lane5:U-87MG whole cell lysate (40ug) Lane6:HepG2 whole cell lysate (40ug) Lane7:Hela whole cell lysate (40ug)
Host or Source
Rabbit

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