E2F4/E2F5 (L50/83) polyclonal antibody

CAT: 0384-BS1095-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS1095-01Size:50 µL
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Background
E2F was originally identified through its role in transcriptional activation of the adenovirus E2 promoter. Sequences homologous to the E2F binding site have been found upstream of a number of genes that encode proteins with putative functions in the G1 and S phases of the cell cycle. E2F-1 is a member of a broader family of transcriptional regulators including E2F-2, E2F-3, E2F-4, E2F-5 and E2F-6, each of which forms heterodimers with a second protein, DP-1, forming an “active” E2F transcriptional regulatory complex.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Transcription factor E2F4; E2F-4; E2F4; Transcription factor E2F5; E2F-5; E2F5
Swiss Prot
Q16254 / Q15329
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 18-72 of Human E2F4.
Conjugation
Unconjugated
Related Pathways
Cell Cycle Control G1 S Checkpoint
Applications
IHC
Dilution
IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 44 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
E2F4/E2F5 (L50/83) polyclonal antibody detects endogenous levels of E2F4/E2F5 protein.
Host or Source
Rabbit

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