Products for Research Use Only
RegisterLogin

APC (Q2829) polyclonal antibody

CAT: 0384-BS1017-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0384-BS1017-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Adenomatous polyposis coli (APC) is a protein that plays a critical role in several cellular processes. APC is a tumor suppressor, regulates cell division, helps ensure that the number of chromosomes in a cell is correct following cell division and associates with other proteins involved in cell attachment and signaling. APC regulates ß-catenin levels through Wnt-signaling and is involved in actin cytoskeletal integrity, cell-cell adhesion and cell migration. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Adenomatous polyposis coli protein; Protein APC; Deleted in polyposis 2.5; APC; DP2.5
Swiss Prot
P25054
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to the C-terminal of Human APC.
Conjugation
Unconjugated
Related Pathways
Regulation of Microtubule Dynamics, Contribution of Soluble Factors to EMT
Applications
IHC
Dilution
IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 310 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
APC (Q2829) polyclonal antibody detects endogenous levels of APC protein.
Host or Source
Rabbit

Related Products

CatalogName
BS66127APC polyclonal antibody
BS78389-01APC polyclonal antibody
BS90066APC polyclonal antibody
BS90067APC polyclonal antibody
BS1507APC (K2050) polyclonal antibody
BS4649-01APC (phospho-S2054) polyclonal antibody
MB11920APC monoclonal antibody
MB66421APC Rabbit monoclonal antibody
BS6527-01APCS polyclonal antibody
BS90068APC6 polyclonal antibody

Alternative Products

CatalogName
GTR18040884-01APC (Q2829) polyclonal antibody
APR12525GPolyclonal MeCP2 polyclonal antibody
APR00376GPolyclonal BMI1 polyclonal antibody
APR00459GPolyclonal CHD4 polyclonal antibody
APR00451GPolyclonal SPI1 polyclonal antibody
APR00373GPolyclonal EzH2 polyclonal antibody
APR14018GPolyclonal YY1 polyclonal antibody
PTX18700-100UCN3 Polyclonal Polyclonal Antibody
PTX18688-100TKT Polyclonal Polyclonal Antibody
PTX18684-100TGFA Polyclonal Polyclonal Antibody

Popular Products