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ITGAX polyclonal antibody

CAT: 0384-BS61341-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS61341-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CD11c (integrin αX, ITGAX) is a transmembrane glycoprotein that forms an α/β heterodimer with CD18 (integrin β2), which interacts with a variety of extracellular matrix molecules and cell surface proteins. CD11c is primarily used as a dendritic cell marker. Dendritic cells can be classified into two major types: CD11c+ conventional dendritic cells that specialize in antigen presentation, and CD11c- plasmacytoid dendritic cells that specialize in type I interferon production. CD11c expression has also been observed on activated NK cells, subsets of B cells, monocytes, granulocytes, and some B cell malignancies including hairy cell leukemia.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
Integrin alpha-X; CD11 antigen-like family member C; Leu M5; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; CD11c; ITGAX; CD11C
Swiss Prot
P20702
Reactivity
Human
Immunogen
Synthetic peptide, corresponding to Human ITGAX.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 145 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
ITGAX polyclonal antibody detects endogenous levels of ITGAX protein.
Applications Notes
Western blot (WB) analysis of ITGAX polyclonal antibody at 1:500 dilution Lane1:U-87MG whole cell lysate (40ug) Lane2:A549 whole cell lysate (40ug) Lane3:Myla2059 whole cell lysate (40ug)
Host or Source
Rabbit

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