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NDRG3 polyclonal antibody

CAT: 0384-BS62436-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS62436-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The NDRG (N-Myc downstream-regulated gene) family consisting of NDRG1, NDRG2, NDRG3, and NDRG4 are structurally related proteins with roles in cell proliferation, differentiation, apoptosis, stress responses, and cell migration/metastasis. NDRG1 was originally identified as a protein that was upregulated in N-Myc knockout mice. Proteins in the NDRG family, particularly NDRG1 and NDRG2, have been reported to be down-regulated in various cancer tissues and have been suggested to function as a tumor suppressors. Members of the NDRG family each have distinct expression patterns; NDRG3 is most highly expressed in the testis, prostate, ovary, and brain. NDRG3 has also been shown to be up-regulated by androgen in prostate cell lines and can promote cell growth in those cells.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.
Product Name Alternative
Protein NDRG3; N-myc downstream-regulated gene 3 protein; NDRG3
Swiss Prot
Q9UGV2
Reactivity
Human, Mouse
Immunogen
Synthetic peptide, corresponding to Human NDRG3.
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB:1:500~1:1000 IHC:1:50~1:200
Purity
The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 43 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -25°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
NDRG3 polyclonal antibody detects endogenous levels of NDRG3 protein.
Applications Notes
Western blot (WB) analysis of NDRG3 polyclonal antibody at 1:500 dilution LaneA:The brain tissue lysate of Mouse
Host or Source
Rabbit

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