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GPR158 polyclonal antibody

CAT: 0384-BS62572-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS62572-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
G-protein coupled receptor 158 (GPR158) is a receptor belonging to the Class C GPCR family. It lacks the extracellular Venus flytrap module characteristic of the known members of that family and instead contains two other elements that are not typical of the class: a calcium-binding EGF-like domain and a leucine repeat region. The mature extracellular domain of human GPR158 contains 393 amino acids (aa) and shares 89% identity with both mouse and rat GPR158. GPR158 is expressed at the highest level in the brain, but also in a variety of other tissues including retina, spleen, liver and lung. GPR158 was originally identified in functional screens linked with biological stress and has been implicated in the osteocalcin effect on cognitive processes in the brain, and glaucoma and cancer in the periphery.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Probable G-protein coupled receptor 158; GPR158; KIAA1136
Swiss Prot
Q5T848
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to Human GPR158.
Conjugation
Unconjugated
Applications
WB IHC IF
Dilution
WB:1:500~1:1000 IHC:1:50~1:200 IF:1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 150 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
GPR158 polyclonal antibody detects endogenous levels of GPR158 protein.
Applications Notes
Western blot (WB) analysis of GPR158 polyclonal antibody at 1:500 dilution LaneA:BV2 whole cell lysate LaneB:PMVEC whole cell lysate LaneC:A549 whole cell lysate LaneD:HepG2 whole cell lysate
Host or Source
Rabbit

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