CDC42EP5 polyclonal antibody

• Background:

  Cdc42 effector protein 5, probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts. Inhibits MAPK8 independently of CDC42 binding. Controls septin organization and this effect is negatively regulated by CDC42.

• Structure Composition:

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  Cdc42 effector protein 5; Binder of Rho GTPases 3; CDC42EP5; BORG3; CEP5

• Swiss Prot:

  Q6NZY7

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic peptide, corresponding to Human CDC42EP5.

• Conjugation:

  Unconjugated

• Applications:

  WB IHC

• Dilution:

  WB:1:500~1:1000 IHC:1:50~1:200

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodification

• Molecular Weight:

  ~ 19 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  CDC42EP5 polyclonal antibody detects endogenous levels of CDC42EP5 protein.

• Applications Notes:

  Western blot (WB) analysis of CDC42EP5 polyclonal antibody at 1:500 dilution LaneA:CT26 whole cell lysate LaneB:PC12 whole cell lysate LaneC:HepG2 whole cell lysate LaneD:A549 whole cell lysate

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4