NAP1 polyclonal antibody

• Background:

  Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity. Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFNB promoter activation via TICAM1.

• Structure Composition:

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  5-azacytidine-induced protein 2; NF-kappa-B-activating kinase-associated protein 1; Nak-associated protein 1; TILP; AZI2; NAP1; TBKBP2

• Swiss Prot:

  Q9H6S1

• Reactivity:

  Human

• Immunogen:

  Synthetic peptide, corresponding to Human NAP1.

• Conjugation:

  Unconjugated

• Applications:

  WB IHC IF

• Dilution:

  WB:1:500~1:1000 IHC:1:50~1:200 IF:1:50~1:200

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodification

• Molecular Weight:

  ~ 28 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  NAP1 polyclonal antibody detects endogenous levels of NAP1 protein.

• Applications Notes:

  Western blot analysis of extracts of HepG2 cell line, using NAP1 polyclonal antibody.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4