GP1BA polyclonal antibody

• Background:

  CD42a is a single-chain membrane glycoprotein that forms a noncovalent complex with CD42b. CD42b, also known as glycoprotein Ib a (GPIb a) is a membrane glycoprotein that is composed of a and b chains. The CD42b b chain is also designated CD42c, and is expressed on platelets and megakaryocytes. CD42a and CD42b are also present on platelets and mega-karyocytes, and the complex is a major component of the platelet surface. The complex acts as a receptor for von Willebrand’s factor and as a von Willebrand’s factor-dependent adhesion receptor.

• Structure Composition:

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  Platelet glycoprotein Ib alpha chain; GP-Ib alpha; GPIb-alpha; GPIbA; Glycoprotein Ibalpha Antigen CD42b-alpha; CD_antigen=CD42b; GP1BA

• Swiss Prot:

  P07359

• Reactivity:

  Human

• Immunogen:

  A synthetic peptide corresponding to residues in Human GP1BA

• Conjugation:

  Unconjugated

• Applications:

  WB

• Dilution:

  WB: 1:500~1:1000

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodification

• Molecular Weight:

  ~ 100kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  GP1BA polyclonal antibody detects endogenous levels of GP1BA protein.

• Applications Notes:

  Western blot (WB) analysis of GP1BA pAb at 1:500 dilution Lane1:Myla2059 whole cell lysate (40ug) Lane2:SHSY5Y whole cell lysate (40ug) Lane3:SP2/0 whole cell lysate (40ug) Lane4:C6 whole cell lysate (40ug)

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4