MARK2 Polyclonal Antibody

• Background:

  Microtubule affinity regulating kinase 2 (MARK2) Homo sapiens This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]

• Structure Composition:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Product Name Alternative:

  MARK2; EMK1; Serine/threonine-protein kinase MARK2; ELKL motif kinase 1; EMK-1; MAP/microtubule affinity-regulating kinase 2; PAR1 homolog; PAR1 homolog b; Par-1b; Par1b

• Swiss Prot:

  Q7KZI7

• Reactivity:

  Human, Mouse, Rat, Monkey

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human MARK2. AA range:10-59

• Conjugation:

  Unconjugated

• Related Pathways:

  Regulation of Microtubule Dynamics

• Applications:

  WB, IF/ICC, ELISA

• Dilution:

  Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Modification:

  Unmodification

• Molecular Weight:

  ~85 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  MARK2 Polyclonal Antibody detects endogenous levels of MARK2 protein.

• Applications Notes:

  Western Blot analysis of various cells using MARK2 Polyclonal Antibody

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4