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GBRD polyclonal antibody

CAT: 0384-BS65284-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS65284-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Gamma-aminobutyric acid type A receptor delta subunit (GABRD) Homo sapiens Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
CAS Number
9007-83-4
Structure Composition
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Product Name Alternative
GABRD; Gamma-aminobutyric acid receptor subunit delta; GABA (A) receptor subunit delta
Swiss Prot
O14764
Reactivity
Human, Mouse, Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human GABRD. AA range:141-190
Conjugation
Unconjugated
Applications
WB, IHC-p, IF (paraffin section), ELISA
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Modification
Unmodification
Molecular Weight
~ 51 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
GABAA Rδ Polyclonal Antibody detects endogenous levels of GABAA Rδ protein.
Applications Notes
Western blot analysis of lysates from LOVO and HT-29 cells, using GABRD Antibody. The lane on the right is blocked with the synthesized peptide.
Host or Source
Rabbit

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