GDF7 polyclonal antibody

CAT: 0384-BS65262-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS65262-01Size:50 µL
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Background
Growth differentiation factor 7 (GDF7) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in the differentiation of tendon cells and spinal cord interneurons. A mutation in this gene may be associated with increased risk for Barrett's esophagus and esophageal adenocarcinoma. [provided by RefSeq, Sep 2016]
CAS Number
9007-83-4
Structure Composition
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Product Name Alternative
GDF7; Growth/differentiation factor 7; GDF-7
Swiss Prot
Q7Z4P5
Reactivity
Human, Mouse, Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human GDF7. AA range:321-370
Conjugation
Unconjugated
Applications
WB, IHC-p, IF (paraffin section), ELISA
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Modification
Unmodification
Molecular Weight
~ 47 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
GDF-7 Polyclonal Antibody detects endogenous levels of GDF-7 protein.
Applications Notes
Western Blot analysis of Hela cells using GDF-7 Polyclonal Antibody. Antibody was diluted at 1:1000. Secondary antibody (catalog#: RS0002) was diluted at 1:20000
Host or Source
Rabbit

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