TAOK1 polyclonal antibody

• Background:

  Catalytic activity:ATP + a protein = ADP + a phosphoprotein., function:Phosphorylates MKK3 (By similarity) . Activates the p38 MAP kinase pathway through the specific activation of the upstream MKK3 kinase., PTM:Autophosphorylated., similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily., similarity:Contains 1 protein kinase domain., subunit:Self-associates. Interacts with MKK3., tissue specificity:Highly expressed in the testis, and to a lower extent also expressed in brain, placenta, colon and skeletal muscle.

• Structure Composition:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Product Name Alternative:

  TAOK1; KIAA1361; MAP3K16; MARKK; Serine/threonine-protein kinase TAO1; Kinase from chicken homolog B; hKFC-B; MARK Kinase; MARKK; Prostate-derived sterile 20-like kinase 2; PSK-2; PSK2; Prostate-derived STE20-like kinase 2; Thousand and one

• Swiss Prot:

  Q7L7X3

• Reactivity:

  Human

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human TAOK1. AA range:431-480

• Conjugation:

  Unconjugated

• Related Pathways:

  Signaling Pathways Activating p38 MAP Kinase

• Applications:

  WB, IHC-p, IF (paraffin section), ELISA

• Dilution:

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Modification:

  Unmodification

• Molecular Weight:

  ~ 120 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For

• Specificity:

  PSK2 Polyclonal Antibody detects endogenous levels of PSK2 protein.

• Applications Notes:

  Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using TAOK1 Antibody. The picture on the right is blocked with the synthesized peptide.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4