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HMG17 polyclonal antibody

CAT: 0384-BS65226-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS65226-01Size:50 µL
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Background
High mobility group nucleosomal binding domain 2 (HMGN2) Homo sapiens The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMGN1, the encoded protein may help maintain an open chromatin configuration around transcribable genes. The protein has also been found to have antimicrobial activity against bacteria, viruses and fungi. [provided by RefSeq, Oct 2014]
CAS Number
9007-83-4
Structure Composition
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Product Name Alternative
HMGN2; HMG17; Non-histone chromosomal protein HMG-17; High mobility group nucleosome-binding domain-containing protein 2
Swiss Prot
P05204
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human HMG17 around the phosphorylation site of Ser29. AA range:1-50
Conjugation
Unconjugated
Applications
IHC-p, IF (paraffin section), ELISA
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Modification
Unmodification
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For
Specificity
Phospho-HMG-17 (S29) Polyclonal Antibody detects endogenous levels of HMG-17 protein only when phosphorylated at S29.
Applications Notes
Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100 (4° overnight) . High-pressure and temperature Tris-EDTA, pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
Host or Source
Rabbit

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